For US healthcare professionals only.

Clinical challenges of hemophilia treatment

Nearly 80% of bleeds occur in the joints, causing inflammation that can lead to permanent damage, chronic joint pain, and arthropathy1

Acute Joint Bleed


Target Joint


Hemophilic Arthropathy


>30% of patients with severe hemophilia in their 20s and 30s reported more than 5 bleeds in a 6-month period2*

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*Result extracted from a descriptive analysis of the impact of changes in hemophilia care on the outcomes of 4899 men with severe hemophilia A or B living in the United States, based on prospectively collected data in the Universal Data Collection database between May 1998 and September 2011.2